Nuclear Localization Marker of FOXO3a: Can it be Used to Predict Doxorubicin Response?

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Nuclear Localization Marker of FOXO3a: Can it be Used to Predict Doxorubicin Response?

this, functional studies of FOXO3a could only examine its activity indirectly through checking the expression of its inactive form. FOXO3a has been shown to play an important role in mediating the cytotoxic effects of chemotherapeutic drugs such as doxorubicin (Hui et al., 2008a,b). It has been observed that acquisition of chemoresistance correlated unexpectedly with increased expression and nu...

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ژورنال

عنوان ژورنال: Frontiers in Oncology

سال: 2013

ISSN: 2234-943X

DOI: 10.3389/fonc.2013.00149